LAPTI research interests.

The sea gets deeper as you go further into it.

Venetian proverb according to Nassim Taleb

Чем дальше в лес тем больше дров.

parallel Russian proverb

The main theme of our research is the understanding of how genetic information is decoded from DNA into RNA and into proteins. Someone may find this topic a little strange and argue that we already know how this is happening. Indeed, it is probably common knowledge (at least among sufficiently curious individuals) that RNA molecules are synthesized from their DNA templates according to the rules of complementarity between nucleotides (A <-> T(U) and G <-> C) while proteins are synthesized according to the genetic code, in which triplets of nucleotides specify amino acids in synthesized proteins.

However, Life, with its aptitude to explore the possible to find advantageous, does not tend to be limited by very strict laws. Researchers have documented a significant number of specific alterations (many would prefer the word extension) of the above rules. In most cases such alterations of standard rules are known to serve important biological functions, check out our review on this topic for some examples. In our research we extensively use high-throughtput biochemical techniques (to find out what happens in the cells) and phylogenetic approaches (to find out what is important for the cell).

The language we speak:

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viPVB (2007-2016)